منابع مشابه
Mucoadhesive Microsphere: A Review
The conventional oral dosage forms have regarding the short duration of delivery to system. A controlled release system designed to increase its residence time in stomach with contact with mucosa was achieved by the formulation of mucoadhesive microsphere of the drug. The aim of the present study is to provide an overview of various aspects of mucoadhesive microsp various polymers, preparation ...
متن کاملHollow Microsphere: a Review
The purpose of writing this review on Hollow microspheres is to compile the recent literature with special focus on the principal mechanism of floatation to achieve gastric retention. Hollow microsphere promises to be a potential approach for gastric retention. The recent developments of FDDS including approaches to design single-unit and multiple-unit floating systems, mechanism of floating mi...
متن کاملINTRANASAL THERMOREVERSIBLE MUCOADHESIVE GELS: A Review
Almost 40% of active Pharmaceutical ingredients have low oral bioavailability, high hepatic first-pass metabolism and also less efficient in crossing the blood brain barrier for brain targeting through oral delivery. To overcome this problem the various system such as: nasal spray, gels, emulsions, droplets, suspensions, powders and thermoreversible mucoadhesive gels etc have been studied for n...
متن کاملMucoadhesive Drug Delivery System: A Review
Drug actions can be improved by new drug delivery system, such as mucoadhesive system. This system remains in close contact with the absorption tissue, the mucous membrane, releasing the drug at the action site leading to improvement in both local and systemic effects. There are many routes of mucoadhesive drug delivery system, oral route is the most ancient as well as preferred by patient bein...
متن کاملDevelopment of Floating-Mucoadhesive Microsphere for Site Specific Release of Metronidazole.
PURPOSE The purpose of this study was to develop and evaluate metronidazole loaded floating-mucoadhesive microsphere for sustained drug release at the gastric mucosa. METHODS Alginate gastroretentive microspheres containing metronidazole were prepared by ionic gelation method using sodium bicarbonate as gas forming agent, guar gum as mucoadhesive polymer, and Eudragit L100 as drug release mod...
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ژورنال
عنوان ژورنال: Journal of Current Pharma Research
سال: 2018
ISSN: 2230-7834,2230-7842
DOI: 10.33786/jcpr.2018.v08i02.002